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KMID : 0380020150300010001
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Korean Journal of Biotechnology and Bioengineering
2015 Volume.30 No. 1 p.1 ~ p.10
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Recent Advances in Nanozyme Research for Disease Diagnostics
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Shin Ho-Yun
Yoon Tae-Young
Kim Moon-Il
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Abstract
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Nanomaterial-based artificial enzymes (Nanozymes) have attracted recent attention because of their unique advantageous characteristics such as excellent robustness and stability, low-cost production by facile scale-up, and longterm preservation capability that are critically required as an alternative to natural enzymes. These nanozymes exhibit natural enzyme-like activity, and they have been applied to diverse kinds of detection methods for disease-associated biomolecules such as DNAs, proteins, cells, and small molecules including glucose. To highlight the progress in the field of disease diagnostics using nanozyme, this review discusses many nanozyme-based detection methods categorized by the types of target biomolecules. Finally, we address the current challenges and perspectives for the widespread utilization of nanozyme- based disease diagnostics.
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KEYWORD
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Nanozyme, Disease diagnostics, Biosensing, mmunoassay, Magnetic nanoparticle
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